| Acidity Take item 1.0g, add 20ml water, shake fully and filtration.
Add 2 drops of phenolphthalein indicator in filter liquid. Titrate
with sodium hydroxide(0.1mol/l) and not exceed 0.5ml. Chloride
Take item 0.5g, add 20ml water , shake and filter. Add water
up to 25ml in the filter liquid and examine in accordance
with law(Chinese drug code 1990 version 2 volume appendix
page 48) . Compared it with contral liquid which is prepared
by 8.0ml standard sodium chloride solution , it should not
be more thickness(0.016%)
Barium salt Take item 1.0g and place in the pot crucible.
Add 1g free-water sodium carbonate, charcoal with mini-fire
and become cool after ablazing and burning, then add adequacy
hydrochloric acid in the survivor to dissolve. Neutralize
again with sodium hydroxide and filter. Add water up to 25ml
in the filter liquid and add diluted hydrochloric acid so
as not to take place muddy.
Loss weight by drying Take item and dry
on low pressure at 80℃ up to constant weight. Loss weight
do not exceed to 2.0%(Chinese drug code 1990 version 2 volume
appendix page 55)
Ablazing and burning residue not exceed to 0.2%
Relevant substance Take item and add alcohol
to make 0.05mg/ml liquid as test control liquid. In addition
fetch bile control liquid and add the liquid which is made
by alcohol with 0.05mg/ml liquid as test control. Test according
to thin chromatogram(Chinese drug code 1990 version 2 volume
appendix page 30). Take suction so-said two kinds of liquids
10ul per items , drop the same silica gel lamellar, use chloroform-aether-glacial
acetic acid(4:5:1) as developing agent, then cool dry after
expanding, spurt 10% phosphomolybdic acid-alcolhol liquid,
color after dryness at 105℃ about 5 minutes , examine with
visualize at once. Test solution (if coloration impurity dot
do not exceed to more than 3 and compare one of dot color
with main dot of control liquid ) should be not more dense. |
